Plasma digoxin concentration in children with heart failure.
نویسندگان
چکیده
A dosage schedule for digoxin medication is presented which has proved effective and safe in children of different ages with heart failure due to a variety of cardiac conditions. The plasma digoxin concentrations during maintenance therapy, using this schedule, agree closely with previously reported therapeutic adult plasma concentrations, though the results do not exclude the efficiency and safety of higher doses. A twice-daily dosage regimen is suggested.
منابع مشابه
Inspection of Digoxin level in cardiac heart failure patients refer to Taemin Ejtemai and Shohadaye Ashaer clinic
Background: Heart failure is one of the common cardiovascular diseases and digoxin has the positive effect on it. But unfortunately in spite of its positive effect on heart failure therapeutic and toxic level of it in patients is different and close to each other. The aim of this research was determination of digoxin serum level in failur heart patients. Materials and methods: In this cros...
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To study the changes in electrolyte concentrations in cells of patients with congestive heart failure, we measured the sodium and potassium concentrations in erythrocytes obtained from 34 stabilized patients treated with only digoxin and not with diuretics in order to avoid the effects of miscellaneous drugs and acute water overload. Patients were divided into classes I-III according to the NYH...
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BACKGROUND An endogenous digitalis-like compound in mammals has long been postulated, but only recently has a substance indistinguishable from ouabain been identified in human plasma. Because of the potential significance of such a substance in patients with congestive heart failure, we sought to evaluate the pathophysiology of endogenous ouabain in these individuals. METHODS AND RESULTS Usin...
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ورودعنوان ژورنال:
- British medical journal
دوره 2 5865 شماره
صفحات -
تاریخ انتشار 1973